Schlüsselpublikationen mit Einsatz der QIAseq Technologie

Coronavirus-Forschungsanwendungen

• Liu et al. (2020)
  A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples
• Itokawa, K., Sekizuka, T., Hashino, M., Tanaka, R., and Kuroda, M. (2020)
  A proposal of an alternative primer for the ARTIC Network’s multiplex PCR to improve coverage of SARS-CoV-2 genome sequencing
• Itokawa, K., Sekizuka, T., Hashino, M., Tanaka, R., and Kuroda, M. (2020)
  Disentangling primer interactions improves SARS-CoV-2 genome sequencing by the ARTIC Network’s multiplex PCR
• Maitra, A. et al. (2020)
  Mutations in SARS-CoV-2 viral RNA identified in Eastern India: Possible implications for the ongoing outbreak in India and impact on viral structure and host susceptibility
• Hartley et al. (2020)
  Genomic evidence for a case of reinfection with SARS-CoV-2
• Tillett et al. (2020)
  Genomic surveillance revealed prevalence of unique SARS-CoV-2 variants bearing mutation in the RdRp gene among Nevada patients

DNA-Seq

• Xu, C., Padmanabhan, R.,  Reinecke, F., DiCarlo, J., and Wang, Y. (2020)
  Predicting primer and panel off-target rate in QIAseq targeted DNA panels using convolutional neural networks
• Zou, D. et al. (2020)
  Circulating tumor DNA is a sensitive marker for routine monitoring of treatment response in advanced colorectal cancer
• Paul, D. et al. (2020)
  Phylogenomic analysis of SARS-CoV-2 genomes from western India reveals unique linked mutations

RNA-Seq

• Legøy, T. A. et al. (2020)
  Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signaling
• Coenen-Stass, A. M. L., et al. (2018)

  Evaluation of methodologies for microRNA biomarker detection by next generation sequencing

Multimodale Sequenzierung

• Keup, C. et al. (2020)
  Multimodal targeted deep sequencing of circulating tumor cells and matched cell-free DNA provides a more comprehensive tool to identify therapeutic targets in metastatic breast cancer patients

Epigenetik

• Vos, S., Nawrot, T. S., Martens, D. S., Byun H. M., and , B. G. (2020)
  Mitochondrial DNA methylation in placental tissue: a proof of concept study by means of prenatal environmental stressors 

• Yu, M. C. et al. (2020)
  Differential hypermethylation of the VTRNA2-1 promoter in hepatocellular carcinoma as a prognostic factor: Tumor marker prognostic study

• Fleckhaus, J. and Schneider, P. M. (2020)
  Novel multiplex strategy for DNA methylation-based age prediction from small amounts of DNA via Pyrosequencing