Key publications using Genomic Services

miRNA NGS Seq Service

• Whole blood
Metzger, J.M., Lopez, M.S., Schmidt, J.K., Murphy, M.E., Vemuganti, R., and Emborg M.E. (2020)
Effects of cardiac sympathetic neurodegeneration and PPARγ activation on Rhesus macaque whole blood miRNA and mRNA expression profiles.


• Yoriko Heianza, Qiaochu Xue, Jennifer Rood, George A Bray, Frank M Sacks, Lu Qi (2022)
  Circulating thrifty microRNA is related to insulin sensitivity, adiposity, and energy metabolism in adults with overweight and obesity: the POUNDS Lost trial

• Extracellular vesicles
  Marinaro, F., Gómez-Serrano, M., Jorge, I., Silla-Castro, J.C., Vázquez, J., Sánchez-Margallo, F.M., Blázquez, R., López, E., Álvarez. V., and Casado, J.G. (2019)
  Unraveling the molecular signature of extracellular vesicles from endometrial-derived mesenchymal stem cells: potential modulatory effects and therapeutic applications
  
  

• Pepe, J., Rossi, M., Battafarano, G., Vernocchi, P., Conte, F., Marzano, V., Mariani, E., Mortera, S.L., Cipriani, C., Rana, I., Buonuomo, P.S., Bartuli, A., De Martino, V., Pelle, S., Pascucci, L., Toniolo, R.M., Putignani, L., Minisola, S. and Del Fattore, A. (2022)
  Characterization of Extracellular Vesicles in Osteoporotic Patients Compared to Osteopenic and Healthy Controls

Targeted RNA Seq Service

• Whole blood
  Leonardi, A., Kovalchuk, N., Yin, L., Lauren Endres, L., Sara Evke, S., Nevins, S., Samuel Martin, S., Dedon, P. C., Melendez, J.A., Van Winkle, L., Zhang, Q.-Y., Xinxin Ding, X., and Begley, T.J. (2020)
  The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene.

RNA qPCR Services

• Heart tissue
  Lim, T.B., Aliwarga, E., Luu, T.D.A., Li, Y.P., Ng, S.L., Annadoray, L., Sian, S., Ackers-Johnson, M.A., Foo, R.S.-Y. (2019)
  Targeting the highly abundant circular RNA circSlc8a1 in cardiomyocytes attenuates pressure overload induced hypertrophy.

Whole Transcriptome Seq Service

• Carossino, M., Dini, P., Kalbfleisch, T.S., Loynachan, A.T., Canisso, I.F., Cook, R.F., Timoney, P.J., and Balasuriya, U.B.R. (2019)
  Equine arteritis virus long-term persistence is orchestrated by CD8+ T lymphocyte transcription factors, inhibitory receptors, and the CXCL16/CXCR6 axis

 DNA Isolation Service

• OCT embedded tissue blocks or snap frozen tumors
  Monument, M.J., Johnson, K.M., McIlvaine, E., Abegglen, L., Watkins, W.S., Jorde, L.B., Womer, R.B., Beeler, N., Monovich, L., Lawlor, E.R., Bridge, J.A., Schiffman, J.D., Krailo, M.K., Randall, R.L., and Lessnick, S.L. (2014)
  Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology Group


• DNA extraction from microbiome samples (stool)
  Asnicar, F., et al. (2021)
  Microbiome connections with host metabolism and habitual diet