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λ§žμΆ€ν˜• 닀쀑 λͺ¨λ“œ νŒ¨λ„

κ°•λ ₯ν•œ 라이브러리 λ³€ν™˜ 및 농좕 ν™”ν•™

λ§žμΆ€ν˜• NGS νŒ¨λ„μ„ μ„±κ³΅μ μœΌλ‘œ μ„€κ³„ν•˜λ €λ©΄ μ‹œκ°„, λ…Έλ ₯, λΉ„μš©μ— λŒ€ν•œ λ§‰λŒ€ν•œ νˆ¬μžκ°€ ν•„μš”ν•©λ‹ˆλ‹€. μ œν•œ μš”μ†Œλ‘œλŠ” μ˜¬λ°”λ₯Έ ν‘œμ  식별, μ μ ˆν•œ 섀계 방식 선택, μ„±λŠ₯ μ΅œμ ν™” 등이 있으며, μ œμ‘°μ™€ κ΄€λ ¨λœ κΈ΄ 처리 μ‹œκ°„μ€ 좔가적인 문제λ₯Ό μœ λ°œν•©λ‹ˆλ‹€. λ‹Ήμ‚¬μ˜ 독점적인 QIAseq 단일 프라이머 ν™•μž₯(Single Primer Extension, SPE) κΈ°μˆ μ„ 기반으둜 ν•˜λŠ” λ§žμΆ€ν˜• 닀쀑 λͺ¨λ“œ μ—ΌκΈ°μ„œμ—΄ 뢄석 νŒ¨λ„μ€ κ²¬κ³ ν•œ 라이브러리 λ³€ν™˜ 및 농좕 화학을 μ œκ³΅ν•˜μ—¬ κΈ°μ‘΄ 2개 프라이머 μ•°ν”Œλ¦¬μ½˜ ν™”ν•™μ˜ ν•œκ³„λ₯Ό 극볡할 수 μžˆλ„λ‘ ν•©λ‹ˆλ‹€. λ§žμΆ€ν˜• 닀쀑 λͺ¨λ“œ νŒ¨λ„μ€ κ³ λ„λ‘œ λ³΅μž‘ν•œ 라이브러리λ₯Ό μƒμ„±ν•˜κ³  CEBPA 및 TERT ν”„λ‘œλͺ¨ν„°μ™€ 같이 λ³΅μž‘ν•œ GCκ°€ ν’λΆ€ν•œ μ˜μ—­μ—μ„œλ„ μ™„λ²½ν•œ ν‘œμ  적용 λ²”μœ„λ₯Ό μ œκ³΅ν•˜μ—¬ νƒˆλ½κ³Ό μœ„μŒμ„±μ„ μ΅œμ†Œν™”ν•©λ‹ˆλ‹€. 단일 νŠœλΈŒμ—μ„œ λͺ‡ 개 λ˜λŠ” μ΅œλŒ€ 수백 개의 μœ μ „μž ν‘œμ μ„ ν™•μž₯ κ°€λŠ₯ν•˜κ²Œ λ†μΆ•ν•˜κ³  μž¬ν˜„ κ°€λŠ₯ν•œ μ„±λŠ₯을 μ œκ³΅ν•˜λ―€λ‘œ 섀계 μ΅œμ ν™” μ£ΌκΈ°κ°€ λ‹¨μΆ•λ˜μ–΄ μ œν’ˆ λ‚©ν’ˆκΉŒμ§€ κ±Έλ¦¬λŠ” μ‹œκ°„μ΄ λ‹¨μΆ•λ©λ‹ˆλ‹€.

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