Is there a critical step during upfront sample handling when using the PAXgene Blood RNA MDX kit?

Yes. After removing the supernatant by decanting from the PAXgene Blood RNA Tubes, it is sufficient to dab the rim of the tube 5–10 times with a clean paper towel. Excess drying (such as placing the tubes upside down in a rack or wiping the inner walls of the tube) is not recommended and can have negative effects on the automated procedure.