The optical sensor checks the number and position of the loaded samples and ensures that the rotor adaptors are loaded correctly.

The ultrasonic sensor then confirms whether the buffer is sufficient for the protocol.

Finally, the optical sensor checks that the correct tip type and the number of tips are loaded. The QIAcube Connect then starts the protocol.

When the QIAcube Connect picks up a new tip, it passes it through a tip sensor to ensure that the correct tip type is used.

Lysis buffer is then added to each sample, and the filter tip is discarded.

The samples are incubated in the heatable shaker until lysis is complete.

Lysates are applied to the spin columns in the centrifuge.

The centrifuge lid closes. The centrifugation step enables nucleic acids to bind to the spin-column membrane.

The robotic gripper transfers each spin column from the wash to the elute position.

Elution buffer is applied to each spin column.

The centrifugation step enables elution of nucleic acids from the spin columns into an elution tube.

Run completed appears on the touchscreen and tablet, confirming run completion.

Get push notifications on instrument status so you can respond faster when needed by connecting your instrument to the QIAsphere app.

The UV light ensures effective worktable decontamination after the run.

Learn more about the QIAcube Connect UV-light decontamination procedure in this Application Note.