Dr. Johanna Andersson-Assarsson, a researcher in the Swedish Obese Subjects (SOS) study, where she uses digital PCR technology to examine how copy numbers in a single gene may explain why some people are prone to one of the world’s most complex diseases.
The main challenges that we want to address is the mechanisms behind obesity, why some people become obese, while others do not.
Dr. Johanna Andersson-Assarsson, Department of Molecular and Clinical Medicine, University of Gothenburg
It's technically quite difficult to determine exact copy numbers when working with really variable genes that have high copy numbers.
Dr. Johanna Andersson-Assarsson, Department of Molecular and Clinical Medicine, University of Gothenburg
I use digital PCR because of the resolution. When you have a gene that's really highly variable with a large number of copies, the resolution is just not good enough with quantitative PCR.
Dr. Johanna Andersson-Assarsson, Department of Molecular and Clinical Medicine, University of Gothenburg
October 2020