Circulating tumor cells

You’re faced with a dilemma: there’s a tumor that’s too difficult to reach by surgical biopsy. How can you check if it’s progressing or responding to an intervention? Circulating tumor cells (CTCs) could give you the answer.

CTCs act as seeds of metastasis when shed into the blood by a tumor. Since CTCs mimic the properties of a tumor they can also serve as biomarkers. These biomarkers can give you vital clues about the specifics of a cancer, such as:

Status
Origin
Progression
Response to intervention

So how do you detect and characterize CTCs?

All you need is a blood sample and to follow three key steps to standardize your workflow from preanalytics to analytics.

Workflow

Collection and stabilization

CTCs can degrade quickly so how you collect and preserve them will impact the final result.

Try using our gold-standard blood stabilization tube if you store and transport your samples.

CTC isolation

CTCs are rare so finding them in a high background of normal cells in blood is difficult.

Try using AdnTestSelect to specifically pull out CTCs using a mix of optimized antibodies.

CTC characterization

CTCs are diverse so specificity and sensitivity are key to profiling them at the molecular level.

Try using AdnTestDetect to get accurate gene expression profiles.

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Collect and preserve CTCs

Check out this research poster to learn how to get consistent results from CTCs even after storing blood for 72 hours.

See the results

Exclusive offer

For a limited time only, were giving you the chance to try the new AllPrep DNA/mRNA Nano Kit for free. This kit lets you extract DNA and mRNA from CTCs using one simple workflow.

Apply for free test kit