Fascinating facts about DNA
Molecular Biology Resource Center

Genomic DNA Resource Center

In focus

Simplifying high-molecular Weight DNA extraction for long-read sequencing

Are you thinking of extracting high-molecular weight DNA but don’t know where to start? We prepared a selection guide to help you choose an applicable QIAGEN kit based on your preferred gDNA size and sample type requirement.

View selection guide
High-Molecular Weight DNA
Working with difficult samples

How do you extract high-quality DNA from many tissue types, in different states of decomposition? Optimized methods are the solution, for every sample source.

Wildlife crime: Extracting DNA evidence from degraded samples
Wildlife crime: Extracting DNA evidence from degraded samples
Illegal animal trafficking is a rampant problem in the Philippines. Read how Dr. Ian Fontanilla and his team are using DNA extraction and barcoding to quickly identify stolen animals, proving what species they are and where they came from.
Read article
New Poster: Special considerations in the purification of genomic DNA from various sample types
New Poster: Special considerations in the purification of genomic DNA from various sample types
It is critical to use an optimized method for your sample type. This poster provides an overview of special considerations.
Get poster

Back to Basics

We prepared a wide variety of tools that can help sharpen your DNA skills. Our easy-to-use resources can guide you through the fundamental steps in analyzing DNA.
DNA Bench Guide

DNA Bench Guide

Comprehensive knowledge about how to isolate and quantify high quality DNA. This guide is step-by-step.

Start now


Looking for the right gDNA purification kit?

Categorizing kits by sample source, DNA type and platform, the Selection Wheel helps you choose the right kit quickly.

The blueprint of life, simplified

DNA exists in different forms in animals, plants, bacteria and viruses. This handy poster illustrates the basics of DNA. You can use it to decorate your lab and introduce young students into the fascinating world of molecular biology.

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DNA resource center - Poster
Workflow Configurator, wfc, Luna
Looking for the right extraction kit?
Check out our interactive selection wheels to find the optimal kit for your experiment:
  • DNA and RNA  in one or two elution fractions
  • Genomic DNA

Sample Collection and Disruption

Sample disruption efficiency is crucial to the DNA yields. Which methods are suitable for which sample type? How can more DNA be purified from challenging samples? Our resources explain these in an easy-to-understand way.
Technical Note
Technical Note
PAXgene Saliva Collector
Technical note
Infographic
Infographic
Methods of sample disruption
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Application note
Application note
Microbial gDNA isolation
Application note

DNA Extraction

Explore the procedure of DNA extraction from various sample types through a variety of resources including a series of webinars, a special video and keepsake infographic poster.
Webinar on DNA isolation – Part 1
Webinar on DNA isolation – Part 1
Fundamental concepts and special considerations in gDNA isolation for better insights.
Watch
Webinar on DNA isolation – Part 2
Webinar on DNA isolation – Part 2
Tips and tricks for rapid isolation of genomic DNA from tissue samples.
Watch
Webinar on gDNA from FFPE tissue
Webinar on gDNA from FFPE tissue
The challenges of FFPE sample materials – where does variation in quantity of purified DNA come from?
Watch
QC Workflow

Video: How to purify more DNA from challenging tissues

Dr. Dominic O´Neal explains how QIAamp Fast DNA Tissue Kit, delivers genomic DNA from challenging tissue samples using a rapid combination of mechanical, chemical and enzymatic lysis. The poster presented in the video is available here for download.

Watch video

Quality Control

Following sample disruption and DNA extraction, Quality Control (QC) is a vital element of DNA analysis procedure. Here you can explore some key resources on QC.
Webinar – to see or not to see?…what is in my sample?
Webinar – to see or not to see?…what is in my sample?
Sample analytics for Quality Control and the impact on reliable results.
Watch
Learning hub
Learning hub
Visit our learning hub for everything on Quality Control that you might need to know.
Visit

Remarkable and inspiring DNA stories

DNA Day (April 25) commemorates the discovery and understanding of DNA and the scientific advances that understanding has made possible. We remember the time in 1953 when James Watson, Francis Crick, Maurice Wilkins, Rosalind Franklin and colleagues published papers on the structure of DNA in the journal, Nature.

For DNA Day, we’ve gathered some remarkable stories about DNA research to share with you from all areas of science.

Explore DNA stories

  • QIAwave DNA Blood & Tissue Kit

    QIAwave
    63% less plastic and 42% less cardboard

    For a more eco-friendly alternative to our standard kit for extracting total DNA from animal blood and tissues, cells, yeast, or bacteria.

    Go to product

  • PAXgene Saliva Collector (MBA)

    QIAGEN box
    For non-invasive collection, transport, and storage of human saliva

    Workflow standardization to collect, stabilize, transport and store human saliva for low- to high-throughput DNA extraction and analyses.

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Featured Instruments:

  • TissueLyser II

    TissueLyzer
    For medium- to high-throughput sample disruption for molecular analysis

    Simultaneously disrupts multiple biological samples through high-speed shaking in plastic tubes with stainless steel, tungsten carbide, or glass beads.

    Explore now

  • QIAcube Connect

    QIAcube Connect
    For fully automated nucleic acid extraction with QIAGEN’s spin-column kits

    Advanced digital capabilities and connectivity QIAcube Connect allows research labs to fully automate and track their well-known QIAGEN spin-column extraction and purification protocols – at the push of a button.

    Explore now